The glutamine commute: take the N line and transfer to the A

被引：155

作者：

Chaudhry, FA

Reimer, RJ

Edwards, RH ^{[1
]}

机构：

[1] Univ Calif San Francisco, Sch Med, Dept Neurol, Grad Programs Neurosci Cell Biol & Biomed Sci, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Sch Med, Dept Physiol, Grad Programs Neurosci Cell Biol & Biomed Sci, San Francisco, CA 94143 USA

来源：

JOURNAL OF CELL BIOLOGY | 2002年 / 157卷 / 03期

关键词：

glutamine; system N; system A; glutamate; glutamine-glutamate cycle;

D O I：

10.1083/jcb.200201070

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The transfer of glutamine between cells contributes to signaling as well as to metabolism. The recent identification and characterization of the system N and A family of transporters has begun to suggest mechanisms for the directional transfer of glutamine, and should provide ways to test its physiological significance in diverse processes from nitrogen to neurotransmitter release.

引用

页码：349 / 355

页数：7

共 59 条

[1] Na+ transport by the neural glutamine transporter ATA1
Albers, A
Bröer, A
Wagner, CA
Setiawan, I
Lang, PA
Kranz, EU
Lang, F
Bröer, S
[J]. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2001, 443 (01): : 92 - 101
[2] Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance
Arriza, JL
Eliasof, S
Kavanaugh, MP
Amara, SG
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (08) : 4155 - 4160
[3] Barnett NL, 2000, GLIA, V30, P64, DOI 10.1002/(SICI)1098-1136(200003)30:1<64::AID-GLIA7>3.0.CO
[4] 2-I
[5] Bender D.A., 1975, AMINO ACID METABOLIS
[6] Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism
Bennett, MJ
Marchant, A
Green, HG
May, ST
Ward, SP
Millner, PA
Walker, AR
Schulz, B
Feldmann, KA
[J]. SCIENCE, 1996, 273 (5277) : 948 - 950
[7] BODE BP, 1991, J BIOL CHEM, V266, P7376
[8] BROER A, 2002, AM J PHYSIOL, V539, P3
[9] Glutamine uptake by neurons: Interaction of protons with system a transporters
Chaudhry, FA
Schmitz, D
Reimer, RJ
Larsson, P
Gray, AT
Nicoll, R
Kavanaugh, M
Edwards, RH
[J]. JOURNAL OF NEUROSCIENCE, 2002, 22 (01) : 62 - 72
[10] Coupled and uncoupled proton movement by amino acid transport system N
Chaudhry, FA
Krizaj, D
Larsson, P
Reimer, RJ
Wreden, C
Storm-Mathisen, J
Copenhagen, D
Kavanaugh, M
Edwards, RH
[J]. EMBO JOURNAL, 2001, 20 (24) : 7041 - 7051

← 1 2 3 4 5 6 →