Bio3d: an R package for the comparative analysis of protein structures

被引：1480

作者：

Grant, Barry J. ^{[1
]}

Rodrigues, Ana P. C.

ElSawy, Karim M.

McCammon, J. Andrew

Caves, Leo S. D.

机构：

[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA

[2] Burnham Inst Med Res, La Jolla, CA 92037 USA

[3] Univ York, Dept Biol, York YO10 5YW, N Yorkshire, England

[4] Univ Calif San Diego, Howard Hughes Med Inst, La Jolla, CA 92093 USA

来源：

BIOINFORMATICS | 2006年 / 22卷 / 21期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

MOLECULAR-DYNAMICS;

D O I：

10.1093/bioinformatics/btl461

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An automated procedure for the analysis of homologous protein structures has been developed. The method facilitates the characterization of internal conformational differences and inter-conformer relationships and provides a framework for the analysis of protein structural evolution. The method is implemented in bio3d, an R package for the exploratory analysis of structure and sequence data.

引用

页码：2695 / 2696

页数：2

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