Ultrahigh strength of three-dimensional printed diluted magnesium doping wollastonite porous scaffolds

被引:63
作者
Xie, Jiajun [1 ]
Shao, Huifeng [2 ]
He, Dongshuang [3 ]
Yang, Xianyan [3 ]
Yao, Chunlei [1 ]
Ye, Juan [1 ]
He, Yong [2 ]
Fu, Jianzhong [2 ]
Gou, Zhongru [3 ]
机构
[1] Zhejiang Univ, Affiliated Hosp 2, Sch Med, Zhejiang Prov Key Lab Ophthalmol, Hangzhou 310009, Zhejiang, Peoples R China
[2] Zhejiang Univ, Sch Mech Engn, Zhejiang Prov Key Lab Printing Proc & Equipment 3, Hangzhou 310027, Zhejiang, Peoples R China
[3] Zhejiang Univ, Zhejiang California Int Nanosyst Inst, Hangzhou 310058, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
HIGH MECHANICAL STRENGTH; BIOMEDICAL APPLICATIONS; PHOSPHATE BIOCERAMICS; CERAMIC SCAFFOLDS; GLASS-CERAMICS; BONE REPAIR; GROWTH;
D O I
10.1557/mrc.2015.74
中图分类号
T [工业技术];
学科分类号
120111 [工业工程];
摘要
Beyond the traditional phase conversion or biphase mixing hybrid, we developed the dilute magnesium-doped wollastonite inks and three-dimensional (3D) printing approaches to fabricate the ultrahigh strength bioceramic porous scaffolds. The mechanical strength (>120 MPa) of the porous bioceramics was an order of magnitude higher than the pure wollastonite and other stoichiometric Ca-Mg silicate porous bioceramics. This abnormal but expected improvement in strength in bioceramic scaffolds is equivalent or even superior to the mechanical requirement in load-bearing bone defects. The breakthrough is totally unexpected, and it quickly opens the door for the 3D printing bioceramics manufacture and large-area segmental bone defect repair applications.
引用
收藏
页码:631 / 639
页数:9
相关论文
共 34 条
[1]
3D printing of bone substitute implants using calcium phosphate and bioactive glasses [J].
Bergmann, Christian ;
Lindner, Markus ;
Zhang, Wen ;
Koczur, Karolina ;
Kirsten, Armin ;
Telle, Rainer ;
Fischer, Horst .
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, 2010, 30 (12) :2563-2567
[2]
Structural and material approaches to bone tissue engineering in powder-based three-dimensional printing [J].
Butscher, A. ;
Bohner, M. ;
Hofmann, S. ;
Gauckler, L. ;
Mueller, R. .
ACTA BIOMATERIALIA, 2011, 7 (03) :907-920
[3]
Sintering of calcium phosphate bioceramics [J].
Champion, E. .
ACTA BIOMATERIALIA, 2013, 9 (04) :5855-5875
[4]
Targeting Calcium Magnesium Silicates for Polycaprolactone/Ceramic Composite Scaffolds [J].
Chen, Cong ;
Watkins-Curry, Pilanda ;
Smoak, Mollie ;
Hogan, Katie ;
Deese, Steve ;
McCandless, Gregory T. ;
Chan, Julia Y. ;
Hayes, Daniel J. .
ACS BIOMATERIALS SCIENCE & ENGINEERING, 2015, 1 (02) :94-102
[5]
Sintering dense nanocrystalline ceramics without final-stage grain growth [J].
Chen, IW ;
Wang, XH .
NATURE, 2000, 404 (6774) :168-171
[6]
Manufacture of macroporous β-tricalcium phosphate bioceramics [J].
Descamps, M. ;
Duhoo, T. ;
Monchau, F. ;
Lu, J. ;
Hardouin, P. ;
Hornez, J. C. ;
Leriche, A. .
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, 2008, 28 (01) :149-157
[7]
Freezing as a path to build complex composites [J].
Deville, S ;
Saiz, E ;
Nalla, RK ;
Tomsia, AP .
SCIENCE, 2006, 311 (5760) :515-518
[8]
Freeze casting of hydroxyapatite scaffolds for bone tissue engineering [J].
Deville, Sylvain ;
Saiz, Eduardo ;
Tomsia, Antoni P. .
BIOMATERIALS, 2006, 27 (32) :5480-5489
[9]
Magnesium-containing bioactive polycrystalline silicate-based ceramics and glass-ceramics for biomedical applications [J].
Diba, Mani ;
Goudouri, Ourania-Menti ;
Tapia, Felipe ;
Boccaccini, Aldo R. .
CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE, 2014, 18 (03) :147-167
[10]
Magnesium-Containing Bioactive Glasses for Biomedical Applications [J].
Diba, Mani ;
Tapia, Felipe ;
Boccaccini, Aldo R. ;
Strobel, Leonie A. .
INTERNATIONAL JOURNAL OF APPLIED GLASS SCIENCE, 2012, 3 (03) :221-253