Immobilization of Bis(Bipyridine) BINOL Ligands and Their Use in Chiral Resolution

被引：20

作者：

Bunzen, Jens ^{[1
]}

Kiehne, Ulf ^{[1
]}

Benkhaeuser-Schunk, Christian ^{[1
]}

Luetzen, Arne ^{[1
]}

机构：

[1] Univ Bonn, Kekule Inst Organ Chem & Biochem, D-53121 Bonn, Germany

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 21期

关键词：

CROSS-COUPLING REACTION; METALLOSUPRAMOLECULAR CYLINDERS; SUPRAMOLECULAR CYLINDERS; COORDINATION-COMPOUNDS; DNA; COMPLEXES; 2-CHLOROPYRIDINES; 2,2'-BIPYRIDINES; RECOGNITION; HELICATE;

D O I：

10.1021/ol901958v

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An enantiomerically pure bis(bipyridine) BINOL ligand was synthesized which was functionalized with an iodine substituent in its periphery. Using this halogen function, the ligand was immobilized on a commercially available polystyrene gel via Suzuki cross-coupling. The functionalized gel was found to be effective in the chiral resolution of similar bis(bipyridine) ligands based on a Troger's base core.

引用

页码：4786 / 4789

页数：4

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