Enantioselective synthesis of (+) and (-)-dihydrokawain.

被引：63

作者：

Spino, C ^{[1
]}

Mayes, N ^{[1
]}

Desfosses, H ^{[1
]}

机构：

[1] UNIV S PACIFIC,SCH PURE & APPL SCI,SUVA,FIJI

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 36期

关键词：

D O I：

10.1016/0040-4039(96)01429-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first asymmetric synthesis of (+)- and (-)-Dihydrokawain, an alpha-dihydropyrone isolated from the roots of Piper mythisticum, is reported (+)-Dihydrokawain is the natural product and is of S-configuration. Copyright (C) 1996 Elsevier Science Ltd

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页码：6503 / 6506

页数：4

相关论文

共 23 条

[1] COMPONENTS OF KAVA .7. ABSOLUTE-CONFIGURATION OF KAVA LACTONES [J].

ACHENBACH, H ;

THEOBALD, N .

CHEMISCHE BERICHTE-RECUEIL, 1974, 107 (02) :735-737

[2]

[Anonymous], J AM CHEM SOC, V142, P512

[3]

ANTOGNAZZA P, 1995, Patent No. 96018311

[4] (DIPHENYLPHOSPHINO)-BIHETEROARYLS - THE FIRST EXAMPLE OF A NEW CLASS OF CHIRAL ATROPISOMERIC CHELATING DIPHOSPHINE LIGANDS FOR TRANSITION-METAL-CATALYZED STEREOSELECTIVE REACTIONS [J].

BENINCORI, T ;

BRENNA, E ;

SANNICOLO, F ;

TRIMARCO, L ;

ANTOGNAZZA, P ;

CESAROTTI, E .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (06) :685-686

[5] DIFFERENT ENZYMATIC-REACTIONS OF AN ENANTIOMERIC PAIR - SIMULTANEOUS DUAL KINETIC RESOLUTION OF A KETO ESTER BY BAKERS-YEAST [J].

BROOKS, DW ;

WILSON, M ;

WEBB, M .

JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (11) :2244-2248

[6] ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETIC ACID, A VERSATILE REAGENT FOR DETERMINATION OF ENANTIOMERIC COMPOSITION OF ALCOHOLS AND AMINES [J].

DALE, JA ;

DULL, DL ;

MOSHER, HS .

JOURNAL OF ORGANIC CHEMISTRY, 1969, 34 (09) :2543-&

[7] SYNTHESIS AND LITHIATION OF GAMMA,GAMMA-DIFUNCTIONALIZED KETENE DITHIOACETALS - ACCESS TO A NEW SYNTHETIC EQUIVALENT OF A BETA-HYDROXY-BETA-LITHIOACRYLATE - X-RAY MOLECULAR-STRUCTURE OF 2-(1,3-DITHIAN-2-YLIDENEMETHYL)-1,3-DITHIANE [J].

DZIADULEWICZ, E ;

GILES, M ;

MOSS, WO ;

GALLAGHER, T ;

HARMAN, M ;

HURSTHOUSE, MB .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1989, (10) :1793-1798

[8] RESEARCHES ON ACETYLENIC COMPOUNDS .25. SYNTHESIS OF (+/-)-KAWAIN [J].

FOWLER, EMF ;

HENBEST, HB .

JOURNAL OF THE CHEMICAL SOCIETY, 1950, (DEC) :3642-3645

[9] CATALYTIC, ASYMMETRIC-SYNTHESIS OF THE CARBACEPHEM FRAMEWORK [J].

GUZZO, PR ;

MILLER, MJ .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (17) :4862-4867

[10]

HAENSEL R, 1968, PAC SCI, V22, P293