Vitellogenin induction and brain aromatase activity in adult male and female zebrafish exposed to endocrine disrupters

被引：17

作者：

Andersen, L ^{[1
]}

Bjerregaard, P ^{[1
]}

Korsgaard, B ^{[1
]}

机构：

[1] Univ So Denmark, Inst Biol, DK-5230 Odense, Denmark

来源：

FISH PHYSIOLOGY AND BIOCHEMISTRY | 2003年 / 28卷 / 1-4期

关键词：

Adult Male; Endocrine Disrupter; Flutamid; Aromatase Activity; Ethinylestradiol;

D O I：

10.1023/B:FISH.0000030569.11036.e1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Adult male and female zebrafish were exposed to ethinylestradiol (EE2), methyltestosterone (MT), and Flutamid ( F) for one week. EE2 and MT elevated the vitellogenin (VTG) levels in males significantly compared to controls, while no changes in VTG levels were observed in females. Brain aromatase activity was increased significantly in females exposed to EE2 and F compared to control, where as no significant changes in the activity was found in males.

引用

页码：319 / 321

页数：3

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