Molecular characterization of resistance to macrolides in Bartonella henselae

被引：21

作者：

Biswas, Silpak ^{[1
]}

Raoult, Didier ^{[1
]}

Rolain, Jean-Marc ^{[1
]}

机构：

[1] Univ Mediterranee, Unite Rickettsies, CNRS,Fac Med & Pharm, UMR 6020,IFR 48, F-13385 Marseille 05, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 09期

关键词：

23S RIBOSOMAL-RNA; CAT-SCRATCH DISEASE; IN-VITRO; STREPTOCOCCUS-PNEUMONIAE; ERYTHROMYCIN RESISTANCE; EHRLICHIA-CHAFFEENSIS; MUTATIONS; STREPTOGRAMIN; TELITHROMYCIN; ANTIBIOTICS;

D O I：

10.1128/AAC.00263-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We selected in vitro erythromycin-resistant strains of Bartonella henselae. The mutants obtained had point mutations in domain V of 23S rRNA and/or in ribosomal protein U. One lymph node of a patient with cat-scratch disease had such a mutation in 23S rRNA, suggesting that natural resistant strains may infect humans.

引用

收藏

页码：3192 / 3193

页数：2

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