Condensed states of a semiflexible homopolymer: ordered globules and toroids

被引:18
作者
Cooke, IR
Williams, DRM [1 ]
机构
[1] Australian Natl Univ, Res Sch Phys Sci, Canberra, ACT 0200, Australia
[2] MPI Polymerforsch, D-55128 Mainz, Germany
关键词
DNA condensation; semiflexible polymer; Brownian dynamics simulation; toroids; phase transition;
D O I
10.1016/j.physa.2004.03.039
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We examine the condensed states for a semiflexible polymer in poor solvent as a function of stiffness, focusing on the transition region between globule and torus. Conservative estimates for the upper and lower bounds to the globule-torus transition region are found. These are then used to demonstrate that the polymer globule undergoes considerable changes to its overall morphology and internal packing arrangements for stiffness values outside this transition region. Using a variety of methods we characterize these globular structures as stiffness is varied. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:45 / 52
页数:8
相关论文
共 24 条
[1]  
[Anonymous], 1986, NUMERICAL RECIPES FO
[2]   Monomolecular collapse of plasmid DNA into stable virus-like particles [J].
Blessing, T ;
Remy, JS ;
Behr, JP .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (04) :1427-1431
[3]  
Bloomfield VA, 1997, BIOPOLYMERS, V44, P269, DOI 10.1002/(SICI)1097-0282(1997)44:3<269::AID-BIP6>3.0.CO
[4]  
2-T
[5]   DNA condensation [J].
Bloomfield, VA .
CURRENT OPINION IN STRUCTURAL BIOLOGY, 1996, 6 (03) :334-341
[6]  
CAUSO MS, 2002, CONDMAT0204110
[7]   Cationic silanes stabilize intermediates in DNA condensation [J].
Fang, Y ;
Hoh, JH .
FEBS LETTERS, 1999, 459 (02) :173-176
[8]   A CONSTANT RADIUS OF CURVATURE MODEL FOR THE ORGANIZATION OF DNA IN TOROIDAL CONDENSATES [J].
HUD, NV ;
DOWNING, KH ;
BALHORN, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (08) :3581-3585
[9]   Cryoelectron microscopy of λ phage DNA condensates in vitreous ice:: The fine structure of DNA toroids [J].
Hud, NV ;
Downing, KH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (26) :14925-14930
[10]   Finite chain length effects on the coil-globule transition of stiff-chain macromolecules: A Monte Carlo simulation [J].
Ivanov, VA ;
Paul, W ;
Binder, K .
JOURNAL OF CHEMICAL PHYSICS, 1998, 109 (13) :5659-5669