The Impact of Influenza Vaccination on Hospitalizations and Mortality Among Frail Older People

被引:16
作者
Lee, Wei-Ju [1 ,2 ,3 ]
Chen, Liang-Kung [2 ,4 ,5 ]
Tang, Gau-Jun [1 ]
Lan, Tzuo-Yun [1 ,6 ]
机构
[1] Natl Yang Ming Univ, Inst Hosp & Hlth Care Adm, Taipei 11221, Taiwan
[2] Natl Yang Ming Univ, Inst Publ Hlth, Taipei 11221, Taiwan
[3] Taipei Vet Gen Hosp, Yuan Shan Branch, Div Geriatr Med, Taipei, I Lan County, Taiwan
[4] Natl Yang Ming Univ, Aging & Hlth Res Ctr, Taipei 11221, Taiwan
[5] Taipei Vet Gen Hosp, Ctr Geriatr & Gerontol, Taipei, Taiwan
[6] China Med Univ, Dept Publ Hlth, Taichung, Taiwan
关键词
Influenza vaccination; older adults; hospitalization; death; HEALTH-INSURANCE; ELDERLY-PEOPLE; POPULATION; EFFICACY; SYSTEM; RISK; INFECTION; PROGRAM; TAIWAN;
D O I
10.1016/j.jamda.2013.12.003
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Objectives: The objective of this study was to evaluate the benefits of influenza vaccination against hospitalization and mortality on frail elderly people. Design: The design was a population-based retrospective cohort study. Setting: Taiwan's National Health Insurance claims data. Participants: Participants were 5063 frail seniors, followed up for four years. Measurements: Measurements included age, gender, socioeconomic status, living areas, use of annual health examinations, comorbid conditions, use of influenza vaccine, frailty as defined by the Adjusted Clinical Group, hospitalization, and mortality in the observation period. The efficacy was presented as comparing ever versus never vaccinated people during the entire study period without regard to seasons. Results: Compared with those without influenza vaccination, vaccinated elderly individuals were younger, more likely to be men, have higher socioeconomic status, live in rural areas, have a higher rate of receiving a health examination, and have similar medical conditions. In the Cox proportional hazards analysis, influenza vaccination reduced by 7% the risk of hospitalization (95% confidence interval [CI] 0.86 -0.99) and by 44% the risk of mortality (95% CI 0.51-0.62). Conclusion: Influenza vaccination was effective against hospitalization and mortality among the frail elderly. These results uphold the current universal influenza vaccination policy, and encourage policymakers to adopt strategies to improve vaccination use. (C) 2014 - American Medical Directors Association, Inc. All rights reserved.
引用
收藏
页码:256 / 260
页数:5
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