Indole alkaloids from Alstonia macrophylla

被引:23
作者
Keawpradub, N [1 ]
Houghton, PJ [1 ]
机构
[1] UNIV LONDON KINGS COLL,DEPT PHARM,PHARMACOGNOSY RES LABS,LONDON SW3 6LX,ENGLAND
关键词
Alstonia macrophylla; Apocynaceae; root bark; indole alkaloids; alstomacrophylline; alstomacroline;
D O I
10.1016/S0031-9422(97)00351-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two new bisindole alkaloids, alstomacrophylline and alstomacroline, have been isolated from the root bark of Alstonia macrophylla, along with six known alkaloids, alstonerine, alstophylline, macrocarpamine, alstoumerine, 20-epi-antirhine and villastonine N-oxide. The monomeric indole alkaloid, 20-epi-antirhine, has been isolated for the first time from this species. Structures of the alkaloids were determined by spectroscopic methods, especially 2D NMR. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:757 / 762
页数:6
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