Cracking open cell death in the Drosophila ovary

被引:78
作者
Pritchett, Tracy L. [1 ]
Tanner, Elizabeth A. [2 ]
McCall, Kimberly [1 ]
机构
[1] Boston Univ, Dept Biol, Boston, MA 02215 USA
[2] Boston Univ, Mol Biol Cell Biol & Biochem Program, Boston, MA 02215 USA
关键词
Drosophila; Oogenesis; Apoptosis; Autophagy; Caspase; Insulin; INSULIN-LIKE PEPTIDES; NURSE CELLS; SIGNALING PATHWAY; FOLLICLE CELLS; EGG CHAMBER; GERM-CELLS; OOGENESIS; MELANOGASTER; APOPTOSIS; AUTOPHAGY;
D O I
10.1007/s10495-009-0369-z
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Drosophila melanogaster ovary is a powerful yet simple system with only a few cell types. Cell death in the ovary can be induced in response to multiple developmental and environmental signals. These cell deaths occur at distinct stages of oogenesis and involve unique mechanisms utilizing apoptotic, autophagic and perhaps necrotic processes. In this review, we summarize recent progress characterizing cell death mechanisms in the fly ovary.
引用
收藏
页码:969 / 979
页数:11
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