A simple and sensitive "dipstick" test in serum based on lateral flow separation of aptamer-linked nanostructures"

被引：275

作者：

Liu, Juewen ^{[1
]}

Mazumdar, Debapriya ^{[1
]}

Lu, Yi ^{[1
]}

机构：

[1] Univ Illinois, Beckman Inst Adv Sci & Technol, Dept Chem, Urbana, IL 61801 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 47期

关键词：

aptamers; cocaine; lateral flow; sensors; trace analysis;

D O I：

10.1002/anie.200603106

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) A quick plunge: By using lateral flow devices as a platform to separate aptamer-assembled nanoparticle (NP) aggregates, highly sensitive and selective colorimetric sensors were constructed that mimic litmus paper tests. Detection of cocaine in serum was also realized. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7955 / 7959

页数：5

共 29 条

[1] DNA aptamers and DNA enzymes [J].

Breaker, RR .

CURRENT OPINION IN CHEMICAL BIOLOGY, 1997, 1 (01) :26-31

[2] An enzyme-linked oligonucleotide assay [J].

Drolet, DW ;

MoonMcDermott, L ;

Romig, TS .

NATURE BIOTECHNOLOGY, 1996, 14 (08) :1021-1025

[3] INVITRO SELECTION OF RNA MOLECULES THAT BIND SPECIFIC LIGANDS [J].

ELLINGTON, AD ;

SZOSTAK, JW .

NATURE, 1990, 346 (6287) :818-822

[4] Chemical biology - Aptamers in nanoland [J].

Famulok, M ;

Mayer, G .

NATURE, 2006, 439 (7077) :666-669

[5] Oligonucleotide aptamers that recognize small molecules [J].

Famulok, M .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 1999, 9 (03) :324-329

[6] Oligonucleotide-functionalized gold nanoparticles as probes in a dry-reagent strip biosensor for DNA analysis by hybridization [J].

Glynou, K ;

Ioannou, PC ;

Christopoulos, TK ;

Syriopoulou, V .

ANALYTICAL CHEMISTRY, 2003, 75 (16) :4155-4160

[7] Protein-dependent ribozymes report molecular interactions in real time [J].

Hartig, JS ;

Najafi-Shoushtari, SH ;

Grüne, I ;

Yan, A ;

Ellington, AD ;

Famulok, M .

NATURE BIOTECHNOLOGY, 2002, 20 (07) :717-722

[8] Optical sensors based on hybrid aptamer/conjugated polymer complexes [J].

Ho, HA ;

Leclerc, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (05) :1384-1387

[9] Aptamer-modified gold nanoparticles for colorimetric determination of platelet-derived growth factors and their receptors [J].

Huang, CC ;

Huang, YF ;

Cao, ZH ;

Tan, WH ;

Chang, HT .

ANALYTICAL CHEMISTRY, 2005, 77 (17) :5735-5741

[10] A DNA APTAMER THAT BINDS ADENOSINE AND ATP [J].

HUIZENGA, DE ;

SZOSTAK, JW .

BIOCHEMISTRY, 1995, 34 (02) :656-665

← 1 2 3 →