Rethinking the Hierarchy of Sugar Utilization in Bacteria

被引：26

作者：

Beisel, Chase L. ^{[1
]}

Afroz, Taliman ^{[1
]}

机构：

[1] N Carolina State Univ, Dept Chem & Biomol Engn, Raleigh, NC 27695 USA

来源：

JOURNAL OF BACTERIOLOGY | 2016年 / 198卷 / 03期

基金：

美国国家科学基金会;

关键词：

ESCHERICHIA-COLI; ARABAD PROMOTER; ARABINOSE; XYLOSE; SWITCH;

D O I：

10.1128/JB.00890-15

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

Bacteria are known to consume some sugars over others, although recent work reported by Koirala and colleagues in this issue of the Journal of Bacteriology (S. Koirala, X. Wang, and C. V. Rao, J Bacteriol 198:386-393, 2016, http://dx.doi.org/10.1128/JB.00709-15) revealed that individual cells do not necessarily follow this hierarchy. By studying the preferential consumption of L-arabinose over D-xylose in Escherichia coli, those authors found that subpopulations consume one, the other, or both sugars through cross-repression between utilization pathways. Their findings challenge classic assertions about established hierarchies and can guide efforts to engineer the simultaneous utilization of multiple sugars.

引用

页码：374 / 376

页数：3

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