Toll and interleukin-1 receptor (TIR) domain-containing proteins in plants: a genomic perspective

被引:39
作者
Jebanathirajah, JA [1 ]
Peri, S
Pandey, A
机构
[1] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA
[2] Johns Hopkins Univ, McKusick Nathans Inst Genet Med, Baltimore, MD 21287 USA
关键词
D O I
10.1016/S1360-1385(02)02309-9
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Toll and interleukin-1 receptor (TIR) domains were originally described from comparisons of proteins found in mammals and Drosophila. They are now known to occur in several organisms, with the most TIR proteins being found in Arabidopsis: our analysis of the sequenced Arabidopsis genome has revealed the presence of at least 135 proteins containing TIR domains. Several novel types of TIR-domain-containing proteins are found in Arabidopsis that are not found in other genomes. Here, we discuss the roles of TIR-domain-containing proteins in pathogen resistance and as candidate signaling modules.
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页码:388 / 391
页数:4
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