Myocardial dysfunction in sepsis: no role for NO?

被引：22

作者：

Belcher, E ^{[1
]}

Mitchell, J ^{[1
]}

Evans, T ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Royal Brompton Hosp, Sch Med, Crit Care Unit, London SW3 6NP, England

来源：

HEART | 2002年 / 87卷 / 06期

基金：

英国惠康基金;

关键词：

D O I：

10.1136/heart.87.6.507

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effects of nitric oxide on myocardial function in clinical sepsis are unclear, with studies in experimental models suggesting both beneficial and deleterious effects.

引用

页码：507 / 509

页数：3

共 26 条

[1] INDUCTION OF NO SYNTHASE IN RAT CARDIAC MICROVASCULAR ENDOTHELIAL-CELLS BY IL-1-BETA AND IFN-GAMMA
BALLIGAND, JL
UNGUREANULONGROIS, D
SIMMONS, WW
KOBZIK, L
LOWENSTEIN, CJ
LAMAS, S
KELLY, RA
SMITH, TW
MICHEL, T
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1995, 268 (03): : H1293 - H1303
[2] AMERICAN-COLLEGE OF CHEST PHYSICIANS SOCIETY OF CRITICAL CARE MEDICINE CONSENSUS CONFERENCE - DEFINITIONS FOR SEPSIS AND ORGAN FAILURE AND GUIDELINES FOR THE USE OF INNOVATIVE THERAPIES IN SEPSIS
BONE, RC
BALK, RA
CERRA, FB
DELLINGER, RP
FEIN, AM
KNAUS, WA
SCHEIN, RMH
SIBBALD, WJ
ABRAMS, JH
BERNARD, GR
BIONDI, JW
CALVIN, JE
DEMLING, R
FAHEY, PJ
FISHER, CJ
FRANKLIN, C
GORELICK, KJ
KELLEY, MA
MAKI, DG
MARSHALL, JC
MERRILL, WW
PRIBBLE, JP
RACKOW, EC
RODELL, TC
SHEAGREN, JN
SILVER, M
SPRUNG, CL
STRAUBE, RC
TOBIN, MJ
TRENHOLME, GM
WAGNER, DP
WEBB, CD
WHERRY, JC
WIEDEMANN, HP
WORTEL, CH
[J]. CRITICAL CARE MEDICINE, 1992, 20 (06) : 864 - 874
[3] Brady AJB, 1993, AM J PHYSIOL, P176
[4] THE CORONARY CIRCULATION IN HUMAN SEPTIC SHOCK
CUNNION, RE
SCHAER, GL
PARKER, MM
NATANSON, C
PARRILLO, JE
[J]. CIRCULATION, 1986, 73 (04) : 637 - 644
[5] ENDOTOXEMIA IN HUMAN SEPTIC SHOCK
DANNER, RL
ELIN, RJ
HOSSEINI, JM
WESLEY, RA
REILLY, JM
PARILLO, JE
[J]. CHEST, 1991, 99 (01) : 169 - 175
[6] CYCLIC-AMP PHOSPHODIESTERASES AND CA2+ CURRENT REGULATION IN CARDIAC-CELLS
FISCHMEISTER, R
HARTZELL, HC
[J]. LIFE SCIENCES, 1991, 48 (25) : 2365 - 2376
[7] Has the mortality of septic shock changed with time?
Friedman, G
Silva, E
Vincent, JL
[J]. CRITICAL CARE MEDICINE, 1998, 26 (12) : 2078 - 2086
[8] Biosynthesis of constitutive nitric oxide synthase-derived nitric oxide attenuates coronary vasoconstriction and myocardial depression in a model of septic heart failure induced by Staphylococcus aureus α-toxin
Grandel, U
Sibelius, U
Schrickel, J
Schmidt, D
Buerke, M
Fink, L
Bournelis, E
Heep, M
Mayer, K
Bohle, RM
Seeger, W
Grimminger, F
[J]. CRITICAL CARE MEDICINE, 2001, 29 (01) : 1 - 7
[9] Multi-center, randomized, placebo-controlled, double blind study of the nitric oxide synthase inhibitor 546C88: Effect on survival in patients with septic shock
Grover, R
Lopez, A
Lorente, J
Steingrub, J
Bakker, J
Willatts, S
McLuckie, A
Takala, J
[J]. CRITICAL CARE MEDICINE, 1999, 27 (01) : A33 - A33
[10] An open-label dose escalation study of the nitric oxide synthase inhibitor, NG-methyI-L-arginine hydrochloride (546C88), in patients with septic shock
Grover, R
Zaccardelli, D
Colice, G
Guntupalli, K
Watson, D
Vincent, JL
[J]. CRITICAL CARE MEDICINE, 1999, 27 (05) : 913 - 922

← 1 2 3 →