A 13-year-old girl with recessive dystrophic epidermolysis bullosa presenting with squamous cell carcinoma

被引：17

作者：

Ayman, T

Yerebakan, Ö

Çiftçioglu, MA

Alpsoy, E ^{[1
]}

机构：

[1] Akdeniz Univ, Sch Med, Dept Dermatol, TR-07070 Antalya, Turkey

[2] Akdeniz Univ, Sch Med, Dept Pathol, TR-07070 Antalya, Turkey

来源：

PEDIATRIC DERMATOLOGY | 2002年 / 19卷 / 05期

关键词：

D O I：

10.1046/j.1525-1470.2002.00202.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Recessive dystrophic epidermolysis bullosa (RDEB) is an uncommon and severely disabling genetic disorder characterized by trauma-induced blisters, intractable skin ulcers, scarring, milia, and nail dystrophy. Patients with RDEB have an increased tendency for fast-growing and early metastasizing squamous cell carcinoma (SCC). We report here a 13-year-old girl with RDEB who developed a large SCC on the left knee. At 6 months of evolution it was resected and covered with an autologous skin graft. To our knowledge, this is the youngest patient with RDEB complicated by SCC to be reported, and therefore may serve to emphasize the importance of vigilance in surveying RDEB patients for SCC.

引用

页码：436 / 438

页数：3

共 13 条

[1] Squamous cell carcinoma secondary to recessive dystrophic epidermolysis bullosa: report of eight tumours in four patients [J].