Serum vitamin D level is negatively associated with carotid atherosclerosis in Korean adults

被引：15

作者：

Choi, Yeon-Kyeong ^{[1
]}

Song, Sang-Wook ^{[1
]}

Shin, Bo-Ra ^{[1
]}

Kim, Jeong-Ah ^{[1
]}

Kim, Ha-Na ^{[1
]}

机构：

[1] Catholic Univ Korea, Coll Med, St Vincents Hosp, Dept Family Med, Seoul, South Korea

来源：

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION | 2017年 / 68卷 / 01期

关键词：

Carotid intima-media thickness; carotid plaque; vitamin D deficiency; 25-hydroxyvitamin D; INTIMA-MEDIA THICKNESS; D DEFICIENCY; CARDIOVASCULAR EVENTS; 25-HYDROXYVITAMIN D; PARATHYROID-HORMONE; RISK PREDICTION; T-CELLS; PLAQUE; DISEASE; PREVENTION;

D O I：

10.1080/09637486.2016.1216526

中图分类号：

TS2 [食品工业];

学科分类号：

100403 [营养与食品卫生学];

摘要：

The present study investigated the associations between serum vitamin D levels and carotid intima-media thickness (CIMT), carotid plaque and atherosclerosis in 71 Korean adults. CIMT and the presence of carotid plaque were assessed with a high-resolution B-mode ultrasound system, and carotid atherosclerosis was defined as a mean CIMT value > 0.9mm or the presence of carotid plaque. A vitamin D deficiency was associated with the presence of carotid plaque (adjusted odds ratio [aOR]: 9.25, 95% confidence interval [CI]: 1.52-56.3; p = 0.016). As serum vitamin D levels increased, the presence of high-risk carotid plaque decreased (aOR: 0.84, 95% CI: 0.72-0.99; p = 0.039). Serum vitamin D levels was negatively associated with carotid atherosclerosis (aOR: 0.86, 95% CI: 0.76-0.97; p = 0.018). Further studies are needed to investigate whether vitamin D supplementation would be effective for the prevention of atherosclerosis and cardiovascular diseases.

引用

页码：90 / 96

页数：7

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