Pharmacologic Treatment of Paraphilias

被引：17

作者：

Assumpcao, Alessandra Almeida ^{[1
]}

Garcia, Frederico Duarte ^{[1
,2
]}

Garcia, Heloise Delavenne ^{[1
,2
]}

Bradford, John M. W. ^{[3
]}

Thibaut, Florence ^{[4
,5
,6
]}

机构：

[1] Univ Fed Minas Gerais, INCT Med Mol, Dept Psychiat, BR-30130100 Belo Horizonte, MG, Brazil

[2] Univ Rouen, Rouen Univ Hosp, INSERM, U1073, F-76183 Rouen, France

[3] Univ Ottawa, Brockville Mental Hlth Ctr, Mental Hlth Res Inst, Brockville, ON K6V 5W7, Canada

[4] Univ Hosp Cochin Tarnier, F-75006 Paris, France

[5] Fac Med Paris V Descartes, Dept Psychiat & Addict Disorders, F-75000 Paris, France

[6] INSERM, U894, Ctr Neurosci, F-75000 Paris, France

来源：

PSYCHIATRIC CLINICS OF NORTH AMERICA | 2014年 / 37卷 / 02期

关键词：

Sex offender; Paraphilia; Pedophilia; Selective serotonin reuptake inhibitor; Medroxyprogesterone acetate; Gonadotropin-releasing hormone analogue; Cyproterone acetate; GONADOTROPIN-RELEASING-HORMONE; VIOLENT OFFENDERS; SEXUAL ADDICTIONS; FIRE SETTERS; PEDOPHILIA; AGONIST; RECIDIVISM; TESTOSTERONE; MEDICATIONS; PROFILE;

D O I：

10.1016/j.psc.2014.03.002

中图分类号：

R749 [精神病学];

学科分类号：

100204 [神经病学];

摘要：

The treatment of paraphilias remains a challenge in the mental health field. Combined pharmacologic and psychotherapeutic treatment is associated with better efficacy. The gold standard treatment of severe paraphilias in adult males is antiandrogen treatment with cognitive behavioral therapy. Selective serotonin reuptake inhibitors have been used in mild types of paraphilia and in cases of sexual compulsions and juvenile paraphilias. Antiandrogen treatments seem to be effective in severe paraphilic subjects committing sexual offenses. In particular, gonadotropin-releasing hormone analogs have shown high efficacy working in a similar way to physical castration but being reversible at any time. Treatment recommendations, side effects, and contraindications are discussed.

引用

页码：173 / +

页数：10

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