Neuropathologic findings in a Guillain-Barre patient with strokes after IVIg therapy

被引:22
作者
Byrne, NP
Henry, JC
Herrmann, DN
Abdelhalim, AN
Shrier, DA
Francis, CW
Powers, JM
机构
[1] Univ Rochester, Sch Med & Dent, Dept Pathol & Lab Med Neuropathol, Rochester, NY USA
[2] Univ Rochester, Sch Med & Dent, Dept Med Vasc, Rochester, NY USA
[3] Univ Rochester, Sch Med & Dent, Dept Radiol, Rochester, NY 14642 USA
[4] Univ Rochester, Sch Med & Dent, Dept Neurol, Rochester, NY 14642 USA
关键词
D O I
10.1212/WNL.59.3.458
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Strokes have been rarely associated with immunoglobulin G (IVIg) therapy. A 70-year-old woman with stable polycythemia vera developed Guillain-Barre syndrome and received IVIg, 8 days following which she became comatose due to bilaterally symmetric cerebral infarcts. Autopsy showed intravascular aggregates of fibrin-IgG but also platelets and a necrotizing microangiopathy in the infarcts.
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收藏
页码:458 / 461
页数:4
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