Interactive analysis of selectivity in kinetic resolutions

被引：23

作者：

Goodman, JM ^{[1
]}

Köhler, AK ^{[1
]}

Alderton, SCM ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 49期

关键词：

kinetics; resolution; stereocontrol; computer-assisted methods;

D O I：

10.1016/S0040-4039(99)01850-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Kinetic resolution is a widely used technique, but the mathematical description is awkward to manipulate. This can lead to errors in calculations, and can also make it difficult to assess the effects of the uncertainty in the measurements on the calculated values. This paper presents a convenient method for handling the data generated by kinetic resolution studies. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：8715 / 8718

页数：4

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