Minicolumnar pathology in dyslexia

被引:50
作者
Casanova, MF
Buxhoeveden, DP
Cohen, M
Switala, AE
Roy, EL
机构
[1] Downtown Vet Affairs Med Ctr 24, Augusta, GA 30904 USA
[2] Med Coll Georgia, Dept Psychiat & Neurol, Augusta, GA 30912 USA
[3] Med Coll Georgia, Dept Neurol, Augusta, GA 30912 USA
关键词
D O I
10.1002/ana.10226
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The minicolumn is an anatomical and functional unit of the brain whose genesis accrues from germinal cell divisions in the ventricular zone of the brain. Disturbances in the morphometry of minicolumns have been demonstrated recently for both autism and Down's syndrome. We report minicolumnar abnormalities in the brain of a dyslexic patient. The corresponding developmental disturbance (ie, large minicolumns) could account for the perceptual errors observed in dyslexia.
引用
收藏
页码:108 / 110
页数:3
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