Synthesis of the dichlorobisoxazole-indole portion of the antitumor agent diazonamide by a putative biogenetic strategy

被引：34

作者：

Magnus, P ^{[1
]}

McIver, EG ^{[1
]}

机构：

[1] Univ Texas, Dept Chem & Biochem, Austin, TX 78712 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(99)02203-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chlorination of the bis-oxazole-indole 16 using N-chlorosuccinimide gave the dichloride 13 (86%) and the trichloride 12 (5%) thus completing the synthesis of the CDEF rings of diazonamide. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：831 / 834

页数：4

共 22 条

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