The constituents from the stems of Annona cherimola

Thirty-five compounds including twenty-one alkaloids, lysicamine (1), liriodenine (2), atherospermidine (3), oxoxylopine (4), oxoanolobine (5), oxoglaucine (6), (-)-anonaine (7), (-)-asimilobine (8), (-)-xylopine (9), (-)-anolobine (10), (-)-norisocorydine (11), (+)-laurotetanine (12), (+)-isocorydine (13), (-)-N-methylasimilobine (14), (+)-N-methyllaurotetanine (15), (-)-norushinsunine (16), (-)-ushinsunine (17), (-)-N-formylanonaine (18), (+)-stepharine (19), (+)-orentaline (20), and (-)-kikemanine (21); four kauranes, ent-kaur-16-en-19-oic acid (22), 16 beta-hydroxy-17-acetoxy-ent-kauran-19-al (23), 17-acetoxy-16 beta-ent-kauran-19-oic acid (24), and 16 beta-hydroxy-17-acetoxy-ent-kauran-19-oic acid (25); two amides, N-trans-feruloyltyramine (26), and N-trans-caffeoyltyramine (27); one purine, adenosine (28); one lactam amide, squamolone (29); and six steroids, beta-sitosterol (30), stigmasterol (31), beta-sitostenone (32), stigmasta-4,22-dien-3-one (33), 6 beta-hydroxy-beta-sitosterone (34), and 6 beta-hydroxystigmasterone (35) are isolated from the stems of Annona cherimola. These compounds were characterized and identified by physical and spectral evidence. Among them, (-)-norisocorydine (11) was elucidated as a new enantiomer with a levorotary configuration, which is isolated for the first time.