Treatment of central giant cell granuloma of the jaw with calcitonin

被引：47

作者：

de Lange, J

Rosenberg, AJWP

van den Akker, HP

Koole, R

Wirds, JJ

van den Berg, H

机构：

[1] Univ Amsterdam, Acad Med Ctr, Acad Ctr Dent Amsterdam, Dept Oral & Maxillofacial Surg, NL-1105 AZ Amsterdam, Netherlands

[2] Univ Utrecht Hosp, Dept Oral & Maxillofacial Surg, Utrecht, Netherlands

[3] Med Spectrum Twente, Dept Oral & Maxillofacial Surg, Enschede, Netherlands

[4] Univ Amsterdam, Acad Med Ctr, Dept Pediat Oncol, NL-1105 AZ Amsterdam, Netherlands

来源：

INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 1999年 / 28卷 / 05期

关键词：

central giant cell granuloma; calcitonin; osteoclast;

D O I：

10.1016/S0901-5027(99)80086-1

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Giant cell granuloma of the jaw is a benign lesion that may cause local destruction of bone and displacement of teeth. The common therapy is curettage or resection, which may be associated with loss of teeth and, in younger patients, loss of dental germs, An alternative treatment has recently been introduced, in which patients receive a daily dose of calcitonin. Four patients who have been treated with calcitonin in various concentrations for at least 1 year are reported. in all patients, complete remission of the giant cell granuloma was observed, without signs of recurrence. The working mechanism of calcitonin is discussed, as are length of treatment and optimal dose.

引用

页码：372 / 376

页数：5

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