Update of the LIPID MAPS comprehensive classification system for lipids

被引:1193
作者
Fahy, Eoin [4 ]
Subramaniam, Shankar [3 ]
Murphy, Robert C. [5 ]
Nishijima, Masahiro [6 ]
Raetz, Christian R. H. [7 ]
Shimizu, Takao [8 ]
Spener, Friedrich [9 ]
van Meer, Gerrit [10 ,11 ]
Wakelam, Michael J. O. [12 ]
Dennis, Edward A. [1 ,2 ]
机构
[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Sch Med, Dept Pharmacol, La Jolla, CA 92093 USA
[3] Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA
[4] Univ Calif San Diego, San Diego Supercomp Ctr, La Jolla, CA 92093 USA
[5] Univ Colorado Denver, Dept Pharmacol, Aurora, CO 80045 USA
[6] Natl Inst Hlth Sci, Setagaya Ku, Tokyo 1588501, Japan
[7] Duke Univ, Med Ctr, Dept Biochem, Durham, NC 27710 USA
[8] Univ Tokyo, Fac Med, Dept Biochem & Mol Biol, Tokyo 1130033, Japan
[9] Graz Univ, Dept Mol Biosci, A-8010 Graz, Austria
[10] Univ Utrecht, Bijvoet Ctr, NL-3584 CH Utrecht, Netherlands
[11] Univ Utrecht, Biomembranes Inst, NL-3584 CH Utrecht, Netherlands
[12] Babraham Inst, Cambridge CB22 3AT, England
基金
英国生物技术与生命科学研究理事会; 美国国家卫生研究院;
关键词
lipidomics; nomenclature; structure; databases; DIVERSITY;
D O I
10.1194/jlr.R800095-JLR200
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In 2005, the International Lipid Classification and Nomenclature Committee under the sponsorship of the LIPID MAPS Consortium developed and established a "Comprehensive Classification System for Lipids" based on well-defined chemical and biochemical principles and using an ontology that is extensible, flexible, and scalable. This classification system, which is compatible with contemporary databasing and informatics needs, has now been accepted internationally and widely adopted. In response to considerable attention and requests from lipid researchers from around the globe and in a variety of fields, the comprehensive classification system has undergone significant revisions over the last few years to more fully represent lipid structures from a wider variety of sources and to provide additional levels of detail as necessary.jlr The details of this classification system are reviewed and updated and are presented here, along with revisions to its suggested nomenclature and structure-drawing recommendations for lipids.-Fahy, E., S. Subramaniam, R. C. Murphy, M. Nishijima, C. R. H. Raetz, T. Shimizu, F. Spener, G. vanMeer, M. J. O. Wakelam, and E. A. Dennis. Update of the LIPID MAPS comprehensive classification system for lipids. J. Lipid Res. 2009. S9-S14.
引用
收藏
页码:S9 / S14
页数:6
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