Multiple Mycobacterium tuberculosis strains in early cultures from patients in a high-incidence community setting

被引：65

作者：

Richardson, M

Carroll, NM

Engelke, E

van der Spuy, GD

Salker, F

Munch, Z

Gie, RP

Warren, RM

Beyers, N

van Helden, PD

机构：

[1] Univ Stellenbosch, Dept Biochem Med, MRC, Ctr Mol & Cell Biol,Fac Hlth Sci, ZA-7505 Tygerberg, South Africa

[2] Univ Stellenbosch, Dept Paediat & Child Hlth, Fac Hlth Sci, ZA-7505 Tygerberg, South Africa

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2002年 / 40卷 / 08期

关键词：

D O I：

10.1128/JCM.40.8.2750-2754.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In an ongoing molecular epidemiology study, human immunodeficiency virus-negative patients with first-time pulmonary tuberculosis from a high-incidence community were enrolled. Mycobacterium tuberculosis strains were identified by restriction fragment length polymorphism analysis with two fingerprinting probes. Of 131 patients, 3 (2.3%) were shown to have a mixture of strains in one or two of their serial cultures. This study further investigated these cases with disease caused by multiple M. tuberculosis strains in the context of the molecular epidemiology of the study setting.

引用

页码：2750 / 2754

页数：5

共 15 条

[1]

BATES JH, 1976, AM REV RESPIR DIS, V114, P353

[2] Global dissemination of the Mycobacterium tuberculosis W-Beijing family strains [J].

Bifani, PJ ;

Mathema, B ;

Kurepina, NE ;

Kreiswirth, BN .

TRENDS IN MICROBIOLOGY, 2002, 10 (01) :45-52

[3] Simultaneous infection with multiple strains of Mycobacterium tuberculosis [J].

Braden, CR ;

Morlock, GP ;

Woodley, CL ;

Johnson, KR ;

Colombel, AC ;

Cave, MD ;

Yang, ZH ;

Valway, SE ;

Onorato, IM ;

Crawford, JT .

CLINICAL INFECTIOUS DISEASES, 2001, 33 (06) :E42-E47

[4] Evidence of exogenous reinfection and mixed infection with more than one strain of Mycobacterium tuberculosis among Spanish HIV-infected inmates [J].

Chaves, F ;

Dronda, F ;

Alonso-Sanz, M ;

Noriega, AR .

AIDS, 1999, 13 (05) :615-620

[5] Genetic heterogeneity in Mycobacterium tuberculosis isolates reflected IS6110 restriction fragment length polymorphism patterns as low-intensity bands [J].

de Boer, AS ;

Kremer, K ;

Borgdorff, MW ;

de Haas, PEW ;

Heersma, HF ;

van Soolingen, D .

JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (12) :4478-4484

[6] Demonstration of reinfection and reactivation in HIV-negative autopsied cases of secondary tuberculosis:: multilesional genotyping of Mycobacterium tuberculosis utilizing IS6110 and other repetitive element-based DNA fingerprinting [J].

du Plessis, DG ;

Warren, R ;

Richardson, M ;

Joubert, JJ ;

van Helden, PD .

TUBERCULOSIS, 2001, 81 (03) :211-220

[7] Tuberculosis control and molecular epidemiology in a South African gold-mining community [J].

Godfrey-Faussett, P ;

Sonnenberg, P ;

Shearer, SC ;

Bruce, MC ;

Mee, C ;

Morris, L ;

Murray, J .

LANCET, 2000, 356 (9235) :1066-1071

[8] INSERTION ELEMENT IS987 FROM MYCOBACTERIUM-BOVIS BCG IS LOCATED IN A HOT-SPOT INTEGRATION REGION FOR INSERTION ELEMENTS IN MYCOBACTERIUM-TUBERCULOSIS COMPLEX STRAINS [J].

HERMANS, PWM ;

VANSOOLINGEN, D ;

BIK, EM ;

DEHAAS, PEW ;

DALE, JW ;

VANEMBDEN, JDA .

INFECTION AND IMMUNITY, 1991, 59 (08) :2695-2705

[9] Simultaneous infection with two drug-susceptible Mycobacterium tuberculosis strains in an immunocompetent host [J].

Pavlic, M ;

Allerberger, F ;

Dierich, MP ;

Prodinger, WM .

JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (12) :4156-4157

[10] MIXED-STRAIN INFECTION WITH A DRUG-SENSITIVE AND MULTIDRUG-RESISTANT STRAIN OF MYCOBACTERIUM-TUBERCULOSIS [J].

THEISEN, A ;

REICHEL, G ;

RUSCHGERDES, S ;

HAAS, WH ;

ROCKSTROH, JK ;

SPENGLER, U ;

SAUERBRUCH, T .

LANCET, 1995, 345 (8963) :1512-1513

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