Transferrin-mediated iron acquisition by pathogenic Neisseria

被引:11
作者
Evans, RW [1 ]
Oakhill, JS [1 ]
机构
[1] Kings Coll London, Randall Ctr Mol Mech Cell Funct, Metalloprot Res Grp, London SE1 1UL, England
关键词
iron metabolism; meningococcus; transferrin-binding protein;
D O I
10.1042/bst0300705
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The pathogenic Neisseria have a siderophore-independent iron-uptake system reliant on a direct interaction between the bacterial cell and transferrin. In the meningococcus this uptake system is dependent on two surface-exposed transferring binding proteins. This short account will review our current knowledge of the transferrin-mediated iron-acquisition system of pathogenic Neisseria.
引用
收藏
页码:705 / 707
页数:3
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