A Base-Catalysed One-Pot Three-Component Coupling Reaction Leading to Nitrosubstituted Pyrroles

被引：23

作者：

Baxendale, Ian R. ^{[1
]}

Buckle, Christopher D. ^{[1
]}

Ley, Steven V. ^{[1
]}

Tamborini, Lucia ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Innovat Technol Ctr Adv Chem Synth, Cambridge CB2 1EW, England

来源：

SYNTHESIS-STUTTGART | 2009年 / 09期

关键词：

pyrroles; immobilized reagents; heterocycles; multi-component; MULTISTEP ORGANIC-SYNTHESIS; SOLID-SUPPORTED REAGENTS; EFFICIENT SYNTHESIS; FACILE SYNTHESIS; SCAVENGERS; LIBRARY; PURIFICATION; DERIVATIVES; STRATEGIES; CHEMISTRY;

D O I：

10.1055/s-0028-1087991

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tosyl isocyanide and ethyl chloroformate react with nitrostyrenes to afford nitro-substituted pyrroles in good yield when a catch-and-re lease protocol was employed as a purification strategy.

引用

页码：1485 / 1493

页数：9

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