Preparation and application of functionalized nanoparticles of CdS as a fluorescence probe

被引:54
作者
Wang, L [1 ]
Wang, LY [1 ]
Zhu, CQ [1 ]
Wei, XW [1 ]
Kan, XW [1 ]
机构
[1] Anhui Normal Univ, Coll Chem & Mat Sci, Wuhu, Peoples R China
关键词
nanoparticles; CdS; BSA; fluorescence probe;
D O I
10.1016/S0003-2670(02)00632-3
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
CdS nanoparticles have been prepared and modified with mercaptoacetic acid. The functionalized nanoparticles are water-soluble and biocompatible. They could be used as a fluorescence probe in the determination of bovine serum albumin (BSA), which was proved to be a simple, rapid and specific method. In comparison with single organic fluorophores, these nanoparticle probes are brighter, more stable against photobleaching, and do not suffer from blinking. Under the optimum conditions, the response is linearly proportional to the concentration of BSA between 0.1 and 3.2 mug ml(-1), and the limit of detection is 0.08 mug ml(-1). (C) 2002 Elsevier Science B.V All rights reserved.
引用
收藏
页码:35 / 41
页数:7
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