Successful treatment with nitazoxanide of Enterocytozoon bieneusi microsporidiosis in a patient with AIDS

被引:46
作者
Bicart-Sée, A [1 ]
Massip, P
Linas, MD
Datry, A
机构
[1] Hop Purpan, Serv Malad Infect, Dept Infect & Trop Med, F-31059 Toulouse, France
[2] Rangueil Hosp, Parasitol Mycol Lab, Toulouse, France
[3] Hop La Pitie Salpetriere, Parasitol Mycol Lab, Paris, France
关键词
D O I
10.1128/AAC.44.1.167-168.2000
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A patient with AIDS and chronic diarrhea caused by Enterocytozoon bieneusi was successfully treated with nitazoxanide, producing a complete clinical and parasitological response, while off of antiviral therapy. This suggests that nitazoxanide may be effective in treating microsporidiosis caused by E. bieneusi, a disease for which there is no established treatment.
引用
收藏
页码:167 / 168
页数:2
相关论文
共 12 条
[1]   Severe hepatitis in three AIDS patients treated with indinavir [J].
Brau, N ;
Leaf, HL ;
Wieczorek, RL ;
Margolis, DM .
LANCET, 1997, 349 (9056) :924-925
[2]   Nitazoxanide for the treatment of intestinal protozoan and helminthic infections in Mexico [J].
Cabello, RR ;
Guerrero, LR ;
Garcia, MDM ;
Cruz, AG .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1997, 91 (06) :701-703
[3]   Modification of the clinical course of intestinal microsporidiosis in acquired immunodeficiency syndrome patients by immune status and anti-human immunodeficiency virus therapy [J].
Conteas, CN ;
Berlin, OGW ;
Speck, CE ;
Pandhumas, SS ;
Lariviere, MJ ;
Fu, C .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1998, 58 (05) :555-558
[4]  
Didier ES, 1998, FOLIA PARASIT, V45, P129
[5]   Nitazoxanide in the treatment of cryptosporidial diarrhea and other intestinal parasitic infections associated with acquired immunodeficiency syndrome in tropical Africa [J].
Doumbo, O ;
Rossignol, JF ;
Pichard, E ;
Traore, HA ;
Dembele, M ;
Diakite, M ;
Traore, F ;
Diallo, DA .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1997, 56 (06) :637-639
[6]  
Jeurissen FJF, 1998, AIDS, V12, P441
[7]   Hepatitis C virus-associated hepatitis following treatment of HIV-infected patients with HIV protease inhibitors: an immune restoration disease? [J].
John, M ;
Flexman, J ;
French, MAH .
AIDS, 1998, 12 (17) :2289-2293
[8]   DIAGNOSTIC STRATEGIES IN HIV-INFECTED PATIENTS WITH DIARRHEA [J].
MAYER, HB ;
WANKE, CA .
AIDS, 1994, 8 (12) :1639-1648
[9]   DISSEMINATED MICROSPORIDIOSIS DUE TO SEPTATA-INTESTINALIS IN PATIENTS WITH AIDS - CLINICAL-FEATURES AND RESPONSE TO ALBENDAZOLE THERAPY [J].
MOLINA, JM ;
OKSENHENDLER, E ;
BEAUVAIS, B ;
SARFATI, C ;
JACCARD, A ;
DEROUIN, F ;
MODAI, J .
JOURNAL OF INFECTIOUS DISEASES, 1995, 171 (01) :245-249
[10]   Specific PCR assay for direct detection of intestinal microsporidia Enterocytozoon bieneusi and Encephalitozoon intestinalis in fecal specimens from human immunodeficiency virus-infected patients [J].
Ombrouck, C ;
Ciceron, L ;
Biligui, S ;
Brown, S ;
Marechal, P ;
vanGool, T ;
Datry, A ;
Danis, M ;
DesportesLivage, I .
JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (03) :652-655