Dibutylboron triflate promoted conjugate addition of benzylic and allylic organocopper reagents to chiral alpha,beta-unsaturated N-acyl imidazolidinones

被引：24

作者：

vanHeerden, PS

Bezuidenhoudt, BCB

Ferreira, D

机构：

[1] Department of Chemistry, University of the Orange Free State, Bloemfontein 9300

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(97)00160-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The organocopper-Lewis acid system, RCu-TMEDA-Bu(2)BOTf, is useful for conjugate addition to highly constrained chiral alpha,beta-unsaturated N-acyl imidazolidinones. In comparison with the corresponding TMSCl-activated reagents, Bu(2)BOTf exhibits a dramatic increase in reactivity during 1,4-addition of benzylic and allylic organocopper reagents, which react more readily with crotonoyl-, and especially cinnamoyl imides. (C) 1997 Published by Elsevier Science Ltd.

引用

页码：1821 / 1824

页数：4

共 24 条

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