Cysteine proteases in phytopathogenic bacteria: identification of plant targets and activation of innate immunity

被引：87

作者：

Hotson, A ^{[1
]}

Mudgett, MB ^{[1
]}

机构：

[1] Stanford Univ, Dept Biol Sci, Stanford, CA 94305 USA

来源：

CURRENT OPINION IN PLANT BIOLOGY | 2004年 / 7卷 / 04期

关键词：

D O I：

10.1016/j.pbi.2004.05.003

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytopathogenic bacteria use the type-III secretion system (TTSS) to inject effector proteins into plant cells, presumably to colonize their hosts. The function of these proteins inside plant cells has remained a mystery for years. The recent discovery that the effectors XopD, AvrXv4, AvrPphB, and AvrRpt2 have cysteine protease functions reveals that the proteolysis of host substrates is an important strategy employed by pathogens to alter plant physiology. Moreover, the characterization of these proteases and their targets provides new insight to mechanisms of bacterial virulence and the activation of plant immunity.

引用

收藏

页码：384 / 390

页数：7

相关论文

共 49 条

[1] Pseudomonas type III effector AvrPtoB induces plant disease susceptibility by inhibition of host programmed cell death [J].

Abramovitch, RB ;

Kim, YJ ;

Chen, SR ;

Dickman, MB ;

Martin, GB .

EMBO JOURNAL, 2003, 22 (01) :60-69

[2] Small GTPase 'Rop': molecular switch for plant defense responses [J].

Agrawal, GK ;

Iwahashi, I ;

Rakwal, R .

FEBS LETTERS, 2003, 546 (2-3) :173-180

[3] Genetic and molecular evidence that the Pseudomonas syringae type III effector protein AvrRpt2 is a cysteine protease [J].

Axtell, MJ ;

Chisholm, ST ;

Dahlbeck, D ;

Staskawicz, BJ .

MOLECULAR MICROBIOLOGY, 2003, 49 (06) :1537-1546

[4] Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4 [J].

Axtell, MJ ;

Staskawicz, BJ .

CELL, 2003, 112 (03) :369-377

[5] The Arabidopsis thaliana RPM1 disease resistance gene product is a peripheral plasma membrane protein that is degraded coincident with the hypersensitive response [J].

Boyes, DC ;

Nam, J ;

Dangl, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (26) :15849-15854

[6] The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000 [J].

Buell, CR ;

Joardar, V ;

Lindeberg, M ;

Selengut, J ;

Paulsen, IT ;

Gwinn, ML ;

Dodson, RJ ;

Deboy, RT ;

Durkin, AS ;

Kolonay, JF ;

Madupu, R ;

Daugherty, S ;

Brinkac, L ;

Beanan, MJ ;

Haft, DH ;

Nelson, WC ;

Davidsen, T ;

Zafar, N ;

Zhou, LW ;

Liu, J ;

Yuan, QP ;

Khouri, H ;

Fedorova, N ;

Tran, B ;

Russell, D ;

Berry, K ;

Utterback, T ;

Van Aken, SE ;

Feldblyum, TV ;

D'Ascenzo, M ;

Deng, WL ;

Ramos, AR ;

Alfano, JR ;

Cartinhour, S ;

Chatterjee, AK ;

Delaney, TP ;

Lazarowitz, SG ;

Martin, GB ;

Schneider, DJ ;

Tang, XY ;

Bender, CL ;

White, O ;

Fraser, CM ;

Collmer, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (18) :10181-10186

[7] Genomic approaches in Xanthomonas campestris pv. vesicatoria allow fishing for virulence genes [J].

Büttner, D ;

Noël, L ;

Thieme, F ;

Bonas, U .

JOURNAL OF BIOTECHNOLOGY, 2003, 106 (2-3) :203-214

[8] avrPto enhances growth and necrosis caused by Pseudomonas syringae pv. tomato in tomato lines lacking either Pto or Prf [J].

Chang, JH ;

Rathjen, JP ;

Bernal, AJ ;

Staskawicz, BJ ;

Michelmore, RW .

MOLECULAR PLANT-MICROBE INTERACTIONS, 2000, 13 (05) :568-571

[9] The Pseudomonas syringae avrRpt2 gene product promotes pathogen virulence from inside plant cells [J].

Chen, ZY ;

Kloek, AP ;

Boch, J ;

Katagiri, F ;

Kunkel, BN .

MOLECULAR PLANT-MICROBE INTERACTIONS, 2000, 13 (12) :1312-1321

[10] Assembly and function of type III secretory systems [J].

Cornelis, GR ;

Van Gijsegem, F .

ANNUAL REVIEW OF MICROBIOLOGY, 2000, 54 :735-774

← 1 2 3 4 5 →