Low oestrogen receptor α expression in normal breast tissue underlies low breast cancer incidence in Japan

被引:87
作者
Lawson, JS
Field, AS
Champion, S
Tran, D
Ishikura, H
Trichopoulos, D [1 ]
机构
[1] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[2] Univ New S Wales, Sch Hlth Serv Management, Ctr Publ Hlth, Sydney, NSW, Australia
[3] St Vincents Hosp, Dept Anat Pathol, Sydney, NSW 2010, Australia
[4] Hokkaido Univ, Sch Med, Dept Pathol, Sapporo, Hokkaido 060, Japan
关键词
D O I
10.1016/S0140-6736(99)04936-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Among white Australians without breast cancer, the median of the percentage of oestrogen receptor cr. positive cells was 12% for women younger than 50 years and 17% for those 50 years or older; among Japanese women who had no breast cancer and are generally at low risk for this disease, the corresponding values were both significantly lower and around 9%.
引用
收藏
页码:1787 / 1788
页数:2
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