Chlamydia pneumoniae and hyperlipidemia are co-risk factors for atherosclerosis:: Infection prior to induction of hyperlipidemia does not accelerate development of atherosclerotic lesions in C57BL/6J mice

被引：33

作者：

Blessing, E

Campbell, LA

Rosenfeld, ME

Kuo, CC

机构：

[1] Univ Washington, Dept Pathobiol, Seattle, WA 98195 USA

[2] Univ Washington, Interdisciplinary Grad Program Nutr Sci, Seattle, WA 98195 USA

来源：

INFECTION AND IMMUNITY | 2002年 / 70卷 / 09期

关键词：

D O I：

10.1128/IAI.70.9.5332-5334.2002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Chlamydia pneumoniae has been shown to accelerate atherosclerotic lesion development in hyperlipidemic animals. This study showed that C. pneumoniae did not accelerate lesion development in mice if a high-fat/ high-cholesterol diet was started after infection, indicating that C. pneumoniae is a co-risk factor with hyperlipidemia for cardiovascular disease.

引用

页码：5332 / 5334

页数：3

共 18 条

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