Water:: The ideal hydrogen-atom source in free-radical chemistry mediated by TiIII and other single-electron-transfer metals?

被引：174

作者：

Cuerva, Juan M.

Campana, Araceli G.

Justicia, Jose

Rosales, Antonio

Oller-Lopez, Juan L.

Robles, Rafael

Cardenas, Diego J.

Bunuel, Elena

Oltra, J. Enrique

机构：

[1] Univ Granada, Fac Ciencias, Dept Quim Organ, E-18071 Granada, Spain

[2] Univ Autonoma Madrid, Dept Quim Organ, CI, E-28049 Madrid, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 33期

关键词：

epoxides; hydrogen transfer; radicals; titanium; water;

D O I：

10.1002/anie.200600831

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Hydrogen-atom transfer from water to free radicals can be mediated by aqua complexes of titanium(III) (see scheme). Asymmetric epoxidation in combination with [Cp2TiCl]/H 2O-mediated reductive epoxide opening can be viewed as an alternative with complementary stereoselectivity to the hydroboration-epoxidation method for the enantioselective synthesis of anti-Markovnikov alcohols from alkenes. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：5522 / 5526

页数：5

共 28 条

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