Grape phytochemicals:: A bouquet of old and new nutraceuticals for human health

被引:87
作者
Iriti, Marcello
Faoro, Franco
机构
[1] Univ Milan, Inst Patol Vegetale, I-20133 Milan, Italy
[2] CNR, Ist Virol Vegetale, Dipartimento Agroalimentare, I-20133 Milan, Italy
关键词
D O I
10.1016/j.mehy.2006.03.049
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Health benefits associated with Mediterranean diets are due to the significantly large intake of functional plant foods and beverages, i.e., fruits, vegetables, cereals, legumes, nuts, wine, beer, and olive oil, containing a great array of bioactive phytochemicals or nutraceutical compounds. Therefore, the low risk of chronic diseases, such as coronary hearth disease and certain cancers, observed in some population groups, results from a diversified eating style, either in term of foods and food components. The paradigm of the relationship between the chemical diversity of a particular food and the array of its biological activities may be symbolized by grape. Despite the extensive knowledge about phenylpropanoids, principally polyphenols (stilbenes and anthocyanins) and condensed tannins (proanthocyanidins), in grape and wine, little it is known about the other compounds, such as tetrahydro-beta-carbolines. Recently, it has been attached importance to the dietary indoleamines, metatonin, and serotonin, in different plant foods, including grape, thus further supporting the hypothesis that health benefits, associated with Mediterranean dietary style, are due to plant food chemical diversity. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:833 / 838
页数:6
相关论文
共 44 条
[1]   The chemistry of melatonin's interaction with reactive species [J].
Allegra, M ;
Reiter, RJ ;
Tan, DX ;
Gentile, C ;
Tesoriere, L ;
Livrea, MA .
JOURNAL OF PINEAL RESEARCH, 2003, 34 (01) :1-10
[2]   Neurohormone melatonin prevents cell damage: Effect on gene expression for antioxidant enzymes [J].
Antolin, I ;
Rodriguez, C ;
Sainz, RM ;
Mayo, JC ;
Uria, H ;
Kotler, MI ;
RodriguezColunga, MJ ;
Tolivia, D ;
MenendezPelaez, A .
FASEB JOURNAL, 1996, 10 (08) :882-890
[3]  
AXELROD J, 1961, J BIOL CHEM, V236, P211
[4]  
Badria Farid A., 2002, Journal of Medicinal Food, V5, P153, DOI 10.1089/10966200260398189
[5]   Biogeneration of C13-norisoprenoid compounds:: experiments supportive for an apo-carotenoid pathway in grapevines [J].
Baumes, R ;
Wirth, J ;
Bureau, S ;
Gunata, Y ;
Razungles, A .
ANALYTICA CHIMICA ACTA, 2002, 458 (01) :3-14
[6]   ALKALOIDS IN MAMMALIAN TISSUES .3. CONDENSATION OF L-TRYPTOPHAN AND L-5-HYDROXYTRYPTOPHAN WITH FORMALDEHYDE AND ACETALDEHYDE [J].
BROSSI, A ;
FOCELLA, A ;
TEITEL, S .
JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (04) :418-420
[7]   NEUROBIOLOGY OF TETRAHYDRO-BETA-CARBOLINES [J].
BUCKHOLTZ, NS .
LIFE SCIENCES, 1980, 27 (11) :893-903
[8]   DNA oxidatively damaged by chromium(III) and H2O2 is protected by the antioxidants melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, resveratrol and uric acid [J].
Burkhardt, S ;
Reiter, RJ ;
Tan, DX ;
Hardeland, R ;
Cabrera, J ;
Karbownik, M .
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2001, 33 (08) :775-783
[9]   Detection and quantification of the antioxidant melatonin in montmorency and balaton tart cherries (Prunus cerasus) [J].
Burkhardt, S ;
Tan, DX ;
Manchester, LC ;
Hardeland, R ;
Reiter, RJ .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2001, 49 (10) :4898-4902
[10]   Melatonin in Chinese medicinal herbs [J].
Chen, GF ;
Huo, YS ;
Tan, DX ;
Liang, Z ;
Zhang, WB ;
Zhang, YK .
LIFE SCIENCES, 2003, 73 (01) :19-26