Effect of crude extracts of Erythrina americana Mill. on aggressive behavior in rats

被引：35

作者：

Garín-Aguilar, ME

Luna, JER

Soto-Hernández, M

del Toro, GV

Vázquez, MM

机构：

[1] Colegio Postgrad, Programa Bot, Montecillo 56230, Edo De Mex, Mexico

[2] Univ Nacl Autonoma Mexico, ENEP Iztacala, Tlalnepantla 54690, Edo De Mex, Mexico

[3] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2000年 / 69卷 / 02期

关键词：

Erythrina americana; alkaloids; pharmacology; aggression;

D O I：

10.1016/S0378-8741(99)00121-X

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Three alkaloid fractions were obtained from seeds of Erythrina americana: free alkaloids in hexane, free alkaloids in methanol and liberated alkaloids. The pharmacological evaluation of these fractions on rats showed that, administered in a dose of 3 mg/kg, the three fractions diminished the aggressive behavior. This is comparable when diazepam is used as a control. An interaction between the cholinergic and GABAergic system could be suggested. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：189 / 196

页数：8

共 29 条

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[2]

BRADY J, 1957, J COMP PHYSIOL PSYCH, V96, P339

[3]

ERYTHRINA ALKALOIDS .8. ALKALOIDS IN SEEDS OF 4 ERYTHRINA SPECIES [J].