Dissemination of Carbapenemase-Producing Enterobacteriaceae and Pseudomonas aeruginosa in Romania

被引:37
作者
Dortet, Laurent [1 ,2 ,3 ]
Flonta, Mirela [4 ]
Boudehen, Yves-Marie [2 ]
Creton, Elodie [2 ]
Bernabeu, Sandrine [1 ,2 ,3 ]
Vogel, Anais [2 ]
Naas, Thierry [1 ,2 ,3 ]
机构
[1] Bicetre Hosp, AP HP, Bacteriol Hyg Unit, Le Kremlin Bicetre, France
[2] Univ Paris Sud, Fac Med, LabEx Lermit, F-94275 Le Kremlin Bicetre, France
[3] Associated French Natl Reference Ctr Antibiot Res, Le Kremlin Bicetre, France
[4] Clin Hosp Infect Dis, Microbiol Lab, Cluj Napoca, Romania
关键词
ACINETOBACTER-BAUMANNII; GENETIC FEATURES; RESISTANCE; PLASMID; NDM-1;
D O I
10.1128/AAC.01512-15
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Fifteen carbapenemase-producing Enterobacteriaceae isolates and 12 carbapenemase-producing Pseudomonas aeruginosa isolates were recovered from patients hospitalized between August 2011 and March 2013 at the Hospital of Infectious Disease, ClujNapoca, Romania. One KPC-, nine NDM-1-, four OXA-48-, and one VIM-4-producing Enterobacteriaceae isolates along with 11 VIM-2-producing and one IMP-13-producing P. aeruginosa isolates were recovered from clinical samples. All carbapenemase genes were located on self-conjugative plasmids and were associated with other resistance determinants, including extendedspectrum beta-lactamases and RmtC methylases.
引用
收藏
页码:7100 / 7103
页数:4
相关论文
共 21 条
  • [1] [Anonymous], EURO SURVEILL
  • [2] Characterization of an IncFII Plasmid Encoding NDM-1 from Escherichia coli ST131
    Bonnin, Remy A.
    Poirel, Laurent
    Carattoli, Alessandra
    Nordmann, Patrice
    [J]. PLOS ONE, 2012, 7 (04):
  • [3] Identification of plasmids by PCR-based replicon typing
    Carattoli, A
    Bertini, A
    Villa, L
    Falbo, V
    Hopkins, KL
    Threlfall, EJ
    [J]. JOURNAL OF MICROBIOLOGICAL METHODS, 2005, 63 (03) : 219 - 228
  • [4] Complete sequencing of an IncHI1 plasmid encoding the carbapenemase NDM-1, the ArmA 16S RNA methylase and a resistancenodulationcell division/multidrug efflux pump
    Dolejska, Monika
    Villa, Laura
    Poirel, Laurent
    Nordmann, Patrice
    Carattoli, Alessandra
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2013, 68 (01) : 34 - 39
  • [5] NDM-1, OXA-48 and OXA-181 carbapenemase-producing Enterobacteriaceae in Sultanate of Oman
    Dortet, L.
    Poirel, L.
    Al Yaqoubi, F.
    Nordmann, P.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2012, 18 (05) : E144 - E148
  • [6] Impact of the isolation medium for detection of carbapenemase-producing Enterobacteriaceae using an updated version of the Carba NP test
    Dortet, Laurent
    Brechard, Ludivine
    Poirel, Laurent
    Nordmann, Patrice
    [J]. JOURNAL OF MEDICAL MICROBIOLOGY, 2014, 63 : 772 - 776
  • [7] Rapid Detection of Carbapenemase-Producing Pseudomonas spp.
    Dortet, Laurent
    Poirel, Laurent
    Nordmann, Patrice
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2012, 50 (11) : 3773 - 3776
  • [8] Association of the Emerging Carbapenemase NDM-1 with a Bleomycin Resistance Protein in Enterobacteriaceae and Acinetobacter baumannii
    Dortet, Laurent
    Nordmann, Patrice
    Poirel, Laurent
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 56 (04) : 1693 - 1697
  • [9] Snapshot on carbapenemase-producing Pseudomonas aeruginosa and Acinetobacter baumannii in Bucharest hospitals reveals unusual clones and novel genetic surroundings for blaOXA-23
    Gheorghe, Irina
    Novais, Angela
    Grosso, Filipa
    Rodrigues, Carla
    Chifiriuc, Mariana Carmen
    Lazar, Veronica
    Peixe, Luisa
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2015, 70 (04) : 1016 - 1020
  • [10] Clonal distribution of multidrug-resistant Enterobacter cloacae
    Girlich, Delphine
    Poirel, Laurent
    Nordmann, Patrice
    [J]. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2015, 81 (04) : 264 - 268