Immunocompetence of nestling great tits in relation to rearing environment and parentage

被引:147
作者
Brinkhof, MWG [1 ]
Heeb, P [1 ]
Kölliker, M [1 ]
Richner, H [1 ]
机构
[1] Univ Bern, Dept Zool, Ctr Behav & Evolut, CH-3032 Hinterkappelen, Switzerland
关键词
nestling body mass; Ceratophyllus gallinae; cross-fostering; great tits; cell-mediated immunity; Parus major;
D O I
10.1098/rspb.1999.0925
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Theoretical models of host-parasite coevolution assume a partially genetic basis to the variability in susceptibility to parasites among hosts, for instance as a result of genetic variation in immune function. However, few empirical data exist for free-living vertebrate hosts to support this presumption. In a cross-fostering experiment with nestling great tits, by comparing nestlings of the same origin we investigated (i) the variance in host resistance against an ectoparasite due to a common genetic origin, (ii) the effect of ectoparasite infestation on cell-mediated immunity and (iii) the variance in cell-mediated immunity due to a common genetic origin. Ectoparasitic hen fleas can impair the growth of nestling great tits and nestling growth was therefore taken as a measure of host susceptibility. A common origin did not account for a significant part of the variation in host susceptibility to fleas. There was no significant overall effect of fleas on nestling growth or cell-mediated immunity, as assessed by a cutaneous hypersensitivity response. A common rearing environment explained a significant part of the variation in cell-mediated immunity among nestlings, mainly through its effect on nestling body mass. The variation in cell-mediated immunity was also related to a common origin. However, the origin-related variation in body mass did not account for the origin-related differences in cell-mediated immunity. The results of the present study thus suggest heritable variation in cell-mediated immunity among nestling great tits.
引用
收藏
页码:2315 / 2322
页数:8
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