Allergic hypersensitivity to topical and systemic corticosteroids: a review

被引:82
作者
Baeck, M. [1 ]
Marot, L. [1 ]
Nicolas, J. -F. [2 ]
Pilette, C. [3 ]
Tennstedt, D. [1 ]
Goossens, A. [4 ]
机构
[1] Catholic Univ Louvain, Clin Univ St Luc, Dept Dermatol, B-1200 Brussels, Belgium
[2] Hosp Civiles Lyon, Ctr Lyon Sud, Univ Hosp, Dept Immunoallergol, Lyon, France
[3] Catholic Univ Louvain, Clin Univ St Luc, Dept Pneumol, B-1200 Brussels, Belgium
[4] Katholieke Univ Leuven, Univ Hosp, Dept Dermatol, Leuven, Belgium
关键词
allergic contact dermatitis; corticosteroid; cross-reactions; delayed hypersensitivity; immediate hypersensitivity; METHYLPREDNISOLONE SODIUM SUCCINATE; SEVERE ANAPHYLACTOID REACTION; INFLAMMATORY-BOWEL-DISEASE; BETA-LACTAM ANTIBIOTICS; CONTACT ALLERGY; TIXOCORTOL PIVALATE; DRUG HYPERSENSITIVITY; SERIAL DILUTIONS; INTRAVENOUS CORTICOSTEROIDS; DELAYED-HYPERSENSITIVITY;
D O I
10.1111/j.1398-9995.2009.02038.x
中图分类号
R392 [医学免疫学];
学科分类号
100108 [医学免疫学];
摘要
Corticosteroids, which are potent anti-inflammatory and immunomodulator agents used in the treatment of various inflammatory diseases including allergic diseases, can in some cases produce immediate or delayed hypersensitivity reactions. This review summarizes the epidemiological and clinical characteristics of such reactions, including related diagnostic issues. It also presents a detailed analysis of the proposed immunological mechanisms including underlying cross-reactions.
引用
收藏
页码:978 / 994
页数:17
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