Antimicrobial triterpenes from Debregeasia salicifolia

被引：27

作者：

Akbar, E ^{[1
]}

Malik, A ^{[1
]}

机构：

[1] Univ Karachi, Int Ctr Chem Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan

来源：

NATURAL PRODUCT LETTERS | 2002年 / 16卷 / 05期

关键词：

Debregeasia salicifolia; Urticaceae; triterpenes; antimicrobial activity;

D O I：

10.1080/10575630290033088

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

New triterpene, 3beta-(trans-cinnamoyloxy)-19alpha-hydroxy-urs-12-ene (1) has been isolated from the methanolic fraction of Debregeasia salicifolia, along with uvaol (2), 3beta,19alpha-dihydroxy-urs-12-ene (3), ursolic acid (4), pomolic acid (5), pomolic acid methyl ester (6) and tormentic acid (7) reported for the first time from this species. The compounds (1), (3) and (6) showed significant antimicrobial activity. The structure elucidation was made with the help of extensive 2D NMR spectroscopic techniques.

引用

页码：339 / 344

页数：6

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