High Frequency of Antiretroviral Drug Resistance among HIV-Infected Adults Receiving First-Line Highly Active Antiretroviral Therapy in N'Djamena, Chad

被引：24

作者：

Koyalta, Donato ^{[2
]}

Charpentier, Charlotte ^{[1
,3
]}

Beassamda, Jatibi ^{[2
]}

Rey, Elisabeth ^{[3
,4
]}

Si-Mohamed, Ali ^{[1
,3
]}

Djemadji-Oudjeil, Noel ^{[2
]}

Belec, Laurent ^{[1
,3
]}

机构：

[1] Hop Europeen Georges Pompidou, Virol Lab, F-75015 Paris, France

[2] Hop Gen Reference Natl, Reference Lab, Ndjamena, Chad

[3] Hop St Vincent de Paul, Fac Med Paris Descartes, F-75674 Paris, France

[4] Hop St Vincent de Paul, Serv Pharmacol Clin, Grp Hosp Cochin, F-75674 Paris, France

来源：

CLINICAL INFECTIOUS DISEASES | 2009年 / 49卷 / 01期

关键词：

REGIMEN; AFRICA; PREVALENCE; MUTATIONS; CAMEROON; STRAINS;

D O I：

10.1086/599611

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Antiretroviral drug resistance was evaluated in 88 adults infected with human immunodeficiency virus, most with subtype CRF11_cpx, who had received a first-line antiretroviral regimen for 6 months, in N'Djamena, Chad. A total of 47 patients (53%) had detectable viral load at month 6, and 56 (64%) had at least 1 antiretroviral resistance mutation observed.

引用

页码：155 / 159

页数：5

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