Combination chemotherapy for malignant paraganglioma

被引:15
作者
Kimura, S [1 ]
Iwai, M [1 ]
Fukuda, T [1 ]
Akamatsu, T [1 ]
Ochi, F [1 ]
Masugi, J [1 ]
Nakano, O [1 ]
Sakamoto, T [1 ]
Fukunaga, H [1 ]
Amano, M [1 ]
Fujimori, T [1 ]
Maeda, S [1 ]
机构
[1] NISHIWAKI MUNICIPAL HOSP,DEPT MED,NISHIWAKI,JAPAN
关键词
retroperitoneal tumor; CVD regimen; hepatic metastasis;
D O I
10.2169/internalmedicine.36.35
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Treatment with a combination chemotherapeutic regimen consisting of cyclophosphamide, vincristine, and dacarbazine for malignant paraganglioma with hepatic metastasis is reported, A 51-year-old male presented with tumors in the retroperitoneal space and liver, The patient was diagnosed as having paraganglioma based on elevated levels of serum neuron-specific enolase, urinary catecholamine and vanillylmandelic acid, and on histological findings of the liver specimen, The patient was treated with this combination chemotherapy in repeated 21-day cycles, Temporary improvement in laboratory findings and a 20% reduction in the size of the hepatic masses were observed without severe adverse effects.
引用
收藏
页码:35 / 39
页数:5
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