Antiviral activity of cyclopentenone prostanoids

被引：94

作者：

Santoro, MG ^{[1
]}

机构：

[1] UNIV AQUILA,DEPT EXPT MED,I-67100 LAQUILA,ITALY

来源：

TRENDS IN MICROBIOLOGY | 1997年 / 5卷 / 07期

关键词：

D O I：

10.1016/S0966-842X(97)01066-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cyclopentenone prostanoids inhibit virus replication by turning on an intracellular defence response that involves the induction of cytoprotective heat-shock proteins, the modification of viral glycoprotein maturation and the control of NF-kappa B activation. These molecules represent an interesting model for the development of novel antiviral drugs that can affect different targets during the virus life cycle.

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页码：276 / 281

页数：6

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