Metal insertion into NiFe-hydrogenases

被引:89
作者
Blokesch, M [1 ]
Paschos, A [1 ]
Theodoratou, E [1 ]
Bauer, A [1 ]
Hube, M [1 ]
Huth, S [1 ]
Böck, A [1 ]
机构
[1] Univ Munich, Dept Biol 1, D-80638 Munich, Germany
关键词
auxiliary proteins; carbamoyl phosphate; cyano/carbonyl ligands; endopeptidase; maturation;
D O I
10.1042/BST0300674
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The synthesis and the insertion of the metallocentre of NiFe-hydrogenases is a complex process, in which seven maturation enzymes plus ATP, GTP and carbamoyl phosphate are involved. The review summarizes what is known about the properties and activities of these auxiliary proteins, and postulates a pathway along which maturation may take place.
引用
收藏
页码:674 / 680
页数:7
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