Immune response in cattle vaccinated against rabies

被引：14

作者：

de Oliveira, AN

Andrade, MCR

da Silva, MV

de Moura, WC

Contreiras, EC

机构：

[1] Ctr Controle Zoonoses Paulo Dacorso Filho, BR-23550050 Rio De Janeiro, Brazil

[2] Fdn Oswaldo Cruz, Dept Primatol, Ctr Criacao Anim Lab, Rio De Janeiro, Brazil

[3] Inst Municipal Med Vet Jorge Vaitsman, Lab Raiva & Sorol, Rio De Janeiro, Brazil

[4] Fdn Oswaldo Cruz, Inst Nacl controle Qualidade Saude, Rio De Janeiro, Brazil

[5] Univ Fed Rurale Rio de Janeiro, Dept Microbiol & Imunol, Inst Vet, Seropedica, RJ, Brazil

来源：

MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2000年 / 95卷 / 01期

关键词：

rabies; cattle; vaccination; booster; serology;

D O I：

10.1590/S0074-02762000000100013

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

In order to determine the best type of rabies vaccine to use as a booster, 78 serological samples from singly vaccinated cattle were analyzed by counterimmunoelectrophoresis technique. The animals were divided into several groups, received the first vaccine dose with modified live virus vaccine (ERA strain) and were revaccinated with inactivated virus or modified live virus vaccines. Boosters were given at 2, 4, 8, 12 and 16, weeks following first vaccination. Results showed high titres in the cases of booster with inactivated vaccine. In all cases, however; detectable antibody titres declined quickly.

引用

页码：83 / 88

页数：6

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