Increased coverage of protein families with the Blocks Database servers

被引:226
作者
Henikoff, JG [1 ]
Greene, EA [1 ]
Pietrokovski, S [1 ]
Henikoff, S [1 ]
机构
[1] Fred Hutchinson Canc Res Ctr, Howard Hughes Med Inst, Seattle, WA 98109 USA
关键词
D O I
10.1093/nar/28.1.228
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Blocks Database WWW (http://blocks.fhcrc.org) and Email (blocks@blocks.fhcrc.org) sewers provide tools to search DNA and protein queries against the Blocks+ Database of multiple alignments, which represent conserved protein regions. Blocks+ nearly doubles the number of protein families included in the database by adding families from the Pfam-A, ProDom and Domo databases to those from PROSITE and PRINTS. Other new features include improved Block Searcher statistics, searching with NCBI's IMPALA program and 3D display of blocks on PDB structures.
引用
收藏
页码:228 / 230
页数:3
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