Preparation of polyurethane microcapsules with different soft segments and their characteristics

被引：86

作者：

Hong, K ^{[1
]}

Park, S ^{[1
]}

机构：

[1] Pusan Natl Univ, Dept Text Engn, Pusan 609735, South Korea

来源：

REACTIVE & FUNCTIONAL POLYMERS | 1999年 / 42卷 / 03期

关键词：

polyurethane microcapsules; 2,4-tolylene diisocyanate; poly(ethylene glycol); particle size distributions; release behavior;

D O I：

10.1016/S1381-5148(98)00068-6

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Polyurethane microcapsules were synthesized by interfacial polymerization in an aqueous poly(ethylene glycol) dispersion with ethylene diamine as the chain extender of toluene diisocyanate in perfume oil using poly(vinyl alcohol) as the stabilizing agent. The effects of polyol constituent on the average particle size and distributions, morphologies, loading content and release behavior of polyurethane particles were investigated to design microcapsules for a sustained release system. The release rate of microencapsulated disperse dye molecules became increasingly slow with the molecular weight of polyether polyol. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：193 / 200

页数：8

共 12 条

[1] PAST, PRESENT AND FUTURE-ROLE OF POLYURETHANES FOR SURGICAL IMPLANTS [J].

BORETOS, JW .

PURE AND APPLIED CHEMISTRY, 1980, 52 (07) :1851-1855

[2] THE ROLE OF SURFACTANTS IN SYNTHESIZING POLYUREA MICROCAPSULE [J].

CHAO, DY .

JOURNAL OF APPLIED POLYMER SCIENCE, 1993, 47 (04) :645-651

[3]

FUYAMA H, 1984, J PESTIC SCI, V9, P511

[4] DRUG RELEASE BEHAVIOR FROM POLYURETHANE GEL [J].

KOHJIYA, S ;

IKEDA, Y ;

TAKESAKO, S ;

YAMASHITA, S .

REACTIVE POLYMERS, 1991, 15 :165-175

[5]

KOHJIYA S, 1989, NIHON GOMU KYOKAISHI, V62, P357

[6]

LANGER RS, 1980, BIOMEDICAL POLYM POL, P113

[7] PHYSICOCHEMICAL CHARACTERIZATION AND INVIVO BLOOD TOLERABILITY OF CAST AND EXTRUDED BIOMER [J].

LELAH, MD ;

LAMBRECHT, LK ;

YOUNG, BR ;

COOPER, SL .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1983, 17 (01) :1-22

[8]

REDMAN RP, 1978, DEV POLYURETHANES, pCH3

[9] PREDNISOLONE RELEASE FROM COPOLYURETHANE MONOLITHIC DEVICES [J].

SHARMA, K ;

KNUTSON, K ;

KIM, SW .

JOURNAL OF CONTROLLED RELEASE, 1988, 7 (03) :197-205

[10] MORPHOLOGICAL-CHANGES IN SEGMENTED POLYURETHANE ELASTOMERS BY VARYING THE NCO/OH RATIO [J].

SPATHIS, G ;

NIAOUNAKIS, M ;

KONTOU, E ;

APEKIS, L ;

PISSIS, P ;

CHRISTODOULIDES, C .

JOURNAL OF APPLIED POLYMER SCIENCE, 1994, 54 (07) :831-842

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