An improved method for the palladium-catalyzed amination of aryl triflates

被引：94

作者：

Ahman, J ^{[1
]}

Buchwald, SL ^{[1
]}

机构：

[1] MIT,DEPT CHEM,CAMBRIDGE,MA 02139

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 36期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(97)01464-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aryl triflates are coupled with, amines using catalytic amounts of Pd(OAc)(2) and BINAP and Cs2CO3 as a stoichiometric base. This protocol allows for the efficient amination of electron-poor as well as electron-rich aryl triflates and the reaction conditions are compatible with a wide variety of functional groups. (C) 1997 Elsevier Science Ltd.

引用

页码：6363 / 6366

页数：4

共 6 条

[1] AROMATIC NUCLEOPHILIC-SUBSTITUTION OF HALOBENZENES WITH AMINES UNDER HIGH-PRESSURE [J].