Helicobacter pylori induces AGS cell motility and elongation via independent signaling pathways

被引：63

作者：

Moese, S

Selbach, M

Kwok, T

Brinkmann, V

König, W

Meyer, TF

Backert, S

机构：

[1] Otto Von Guericke Univ, Dept Med Microbiol, D-39120 Magdeburg, Germany

[2] Max Planck Inst Infect Biol, Dept Mol Biol, D-10117 Berlin, Germany

[3] Max Planck Inst Infect Biol, Microscopy Unit, D-10117 Berlin, Germany

来源：

INFECTION AND IMMUNITY | 2004年 / 72卷 / 06期

关键词：

D O I：

10.1128/IAI.72.6.3646-3649.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Helicobacter pylori induces motogenic and cytoskeletal responses in gastric epithelial cells. We demonstrate that these responses can be induced via independent signaling pathways that often occur in parallel. The cag pathogenicity island appears to be nonessential for induction of motility, whereas the elongation phenotype depends on translocation and phosphorylation of CagA.

引用

收藏

页码：3646 / 3649

页数：4

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